Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42
Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and integrates with other signals during early embryogenesis remains poorly understood. We found that the loss of Fak1a impaired epiboly, convergent extension and hypoblast cell...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2020-02-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.190273 |