Identification of a novel resistance (E40F) and compensatory (K43E) substitution in HIV-1 reverse transcriptase
<p>Abstract</p> <p>Background</p> <p>HIV-1 nucleoside reverse transcriptase inhibitors (NRTIs) have been used in the clinic for over twenty years. Interestingly, the complete resistance pattern to this class has not been fully elucidated. Novel mutations in RT appearing...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2008-02-01
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| Series: | Retrovirology |
| Online Access: | http://www.retrovirology.com/content/5/1/20 |