2-Hydroxy-Docosahexaenoic Acid Is Converted Into Heneicosapentaenoic Acid via α-Oxidation: Implications for Alzheimer’s Disease Therapy

2-Hydroxy-Docosahexaenoic Acid Is Converted Into Heneicosapentaenoic Acid via α-Oxidation: Implications for Alzheimer’s Disease Therapy

Alzheimer’s disease (AD) is a neurodegenerative disease with as yet no efficient therapies, the pathophysiology of which is still largely unclear. Many drugs and therapies have been designed and developed in the past decade to stop or slow down this neurodegenerative process, although none has succe...

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Bibliographic Details
Main Authors: Sebastià Parets, Ángel Irigoyen, Margarita Ordinas, Joan Cabot, Marc Miralles, Laura Arbona, Mária Péter, Gábor Balogh, Paula Fernández-García, Xavier Busquets, Victoria Lladó, Pablo V. Escribá, Manuel Torres
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
omega-3 polyunsaturated fatty acids
α-oxidation
Alzheimer’s disease
DHA
hydroxyl derivatives
lipid metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00164/full

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https://www.frontiersin.org/article/10.3389/fcell.2020.00164/full

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