Development of human hepatocellular carcinoma in X-linked severe combined immunodeficient pigs: An orthotopic xenograft model.

Development of human hepatocellular carcinoma in X-linked severe combined immunodeficient pigs: An orthotopic xenograft model.

Hepatocellular carcinoma (HCC) is the fifth most common primary tumor and the third leading cause of cancer-related deaths worldwide. Rodent models of HCC have contributed to the advancement of studies investigating liver carcinogenesis, tumor-host interactions, and drug screening. However, their sm...

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Bibliographic Details
Main Authors: Kohei Mishima, Osamu Itano, Sachiko Matsuda, Shunichi Suzuki, Akira Onishi, Masashi Tamura, Masanori Inoue, Yuta Abe, Hiroshi Yagi, Taizo Hibi, Minoru Kitago, Masahiro Shinoda, Yuko Kitagawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0248352

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https://doi.org/10.1371/journal.pone.0248352

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