Evaluating Methods for Modeling Epistasis Networks with Application to Head and Neck Cancer
Epistasis helps to explain how multiple single-nucleotide polymorphisms (SNPs) interact to cause disease. A variety of tools have been developed to detect epistasis. In this article, we explore the strengths and weaknesses of an information theory approach for detecting epistasis and compare it to t...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2015-01-01
|
| Series: | Cancer Informatics |
| Online Access: | https://doi.org/10.4137/CIN.S17289 |