Heterologous expression of pikromycin biosynthetic gene cluster using Streptomyces artificial chromosome system

Abstract Background Heterologous expression of biosynthetic gene clusters of natural microbial products has become an essential strategy for titer improvement and pathway engineering of various potentially-valuable natural products. A Streptomyces artificial chromosomal conjugation vector, pSBAC, wa...

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Bibliographic Details
Main Authors: Hye-rim Pyeon, Hee-Ju Nah, Seung-Hoon Kang, Si-Sun Choi, Eung-Soo Kim
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-017-0708-7