Heterologous expression of pikromycin biosynthetic gene cluster using Streptomyces artificial chromosome system
Abstract Background Heterologous expression of biosynthetic gene clusters of natural microbial products has become an essential strategy for titer improvement and pathway engineering of various potentially-valuable natural products. A Streptomyces artificial chromosomal conjugation vector, pSBAC, wa...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-05-01
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Series: | Microbial Cell Factories |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12934-017-0708-7 |