A precision medicine approach to defining the impact of doxorubicin on the bioenergetic-metabolite interactome in human platelets

Non-invasive measures of the response of individual patients to cancer therapeutics is an emerging strategy in precision medicine. Platelets offer a potential dynamic marker for metabolism and bioenergetic responses in individual patients since they have active glycolysis and mitochondrial oxidative...

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Bibliographic Details
Main Authors: Matthew Ryan Smith, Balu K. Chacko, Michelle S. Johnson, Gloria A. Benavides, Karan Uppal, Young-Mi Go, Dean P. Jones, Victor M. Darley-Usmar
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719309267