Cross-Protective Shigella Whole-Cell Vaccine With a Truncated O-Polysaccharide Chain

Cross-Protective Shigella Whole-Cell Vaccine With a Truncated O-Polysaccharide Chain

Shigella is a highly prevalent bacterium causing acute diarrhea and dysentery in developing countries. Shigella infections are treated with antibiotics but Shigellae are increasingly resistant to these drugs. Vaccination can be a countermeasure against emerging antibiotic-resistant shigellosis. Beca...

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Bibliographic Details
Main Authors: Min Jung Kim, Young-hye Moon, Heejoo Kim, Semi Rho, Young Kee Shin, Manki Song, Richard Walker, Cecil Czerkinsky, Dong Wook Kim, Jae-Ouk Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Microbiology
Subjects:
Shigella
vaccine
O-antigen polymerase
cross-protection
conserved surface proteins
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02609/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.02609/full

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