Case report: NTRK1-rearranged cervical sarcoma with fibrosarcoma like morphology presenting in a 13-year-old managed with a neo-adjuvant TRK-inhibitor and surgical excision

Case report: NTRK1-rearranged cervical sarcoma with fibrosarcoma like morphology presenting in a 13-year-old managed with a neo-adjuvant TRK-inhibitor and surgical excision

This case report reviews the case of a 13-year-old patient who presented with a 9 cm NTRK1-rearranged cervical sarcoma with fibrosarcoma like morphology. At presentation the lesion filled her vagina and pelvis and any attempt at surgical removal would have been morbid and led to loss of fertility. T...

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Bibliographic Details
Main Authors: E.A. Goulding, P. Morreau, M. De Silva, M. Watson, C. van Vliet, B. Leung, L.J. Eva
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Gynecologic Oncology Reports
Subjects:
NTRK1 fusion
TRK inhibitor
Cervical sarcoma
Fibrosarcoma
Entrectinib
Neo-adjuvant
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578921001491

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http://www.sciencedirect.com/science/article/pii/S2352578921001491

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