Addition of platinum derivatives to neoadjuvant single-agent fluoropyrimidine chemoradiotherapy in patients with stage II/III rectal cancer: protocol for a systematic review and meta-analysis (PROSPERO CRD42017073064)

Addition of platinum derivatives to neoadjuvant single-agent fluoropyrimidine chemoradiotherapy in patients with stage II/III rectal cancer: protocol for a systematic review and meta-analysis (PROSPERO CRD42017073064)

Abstract Background Neoadjuvant (chemo-)radiation has proven to improve local control compared to surgery alone, but this improvement did not translate into better overall or disease-specific survival. The addition of oxaliplatin to fluoropyrimidine-based neoadjuvant chemoradiotherapy holds the pote...

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Bibliographic Details
Main Authors: Felix J. Hüttner, Pascal Probst, Eva Kalkum, Matthes Hackbusch, Katrin Jensen, Alexis Ulrich, Markus W. Büchler, Markus K. Diener
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Systematic Reviews
Subjects:
Rectal cancer
Neoadjuvant therapy
Chemoradiotherapy
Survival
Treatment toxicity
Online Access:http://link.springer.com/article/10.1186/s13643-018-0678-9

Internet

http://link.springer.com/article/10.1186/s13643-018-0678-9

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