Blockade of angiopoietin-2/Tie2 signaling pathway specifically promotes inflammation-induced angiogenesis in mouse cornea

AIM: To investigate angiopoietin-2 (Ang-2)/Tie2 signaling pathway involving in inflammatory angiogenesis. METHODS: Three interrupted 11-0 nylon sutures were placed into the corneal stroma of BALB/c mice (6wk old) to induce inflammatory neovascularization. Expression of Ang-2 and Tie2 protein on neo...

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Bibliographic Details
Main Authors: Zhi-Xin Yan, Yi Luo, Ning-Fei Liu
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2017-08-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.cn/en_publish/2017/8/20170801.pdf