A novel ENU-mutation in ankyrin-1 disrupts malaria parasite maturation in red blood cells of mice.

A novel ENU-mutation in ankyrin-1 disrupts malaria parasite maturation in red blood cells of mice.

The blood stage of the plasmodium parasite life cycle is responsible for the clinical symptoms of malaria. Epidemiological studies have identified coincidental malarial endemicity and multiple red blood cell (RBC) disorders. Many RBC disorders result from mutations in genes encoding cytoskeletal pro...

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Bibliographic Details
Main Authors: Andreas Greth, Shelley Lampkin, Preethi Mayura-Guru, Fleur Rodda, Karen Drysdale, Meredith Roberts-Thomson, Brendan J McMorran, Simon J Foote, Gaétan Burgio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3378575?pdf=render

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http://europepmc.org/articles/PMC3378575?pdf=render

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