Pleiotropic Effects of Immune Responses Explain Variation in the Prevalence of Fibroproliferative Diseases.
Many diseases are differentially distributed among human populations. Differential selection on genetic variants in ancestral environments that coincidentally predispose to disease can be an underlying cause of these unequal prevalence patterns. Selected genes may be pleiotropic, affecting multiple...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2015-11-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC4634921?pdf=render |