The function of heterodimeric AP-1 comprised of c-Jun and c-Fos in activin mediated Spemann organizer gene expression.

BACKGROUND:Activator protein-1 (AP-1) is a mediator of BMP or FGF signaling during Xenopus embryogenesis. However, specific role of AP-1 in activin signaling has not been elucidated during vertebrate development. METHODOLOGY/PRINCIPAL FINDINGS:We provide new evidence showing that overexpression of h...

Full description

Bibliographic Details
Main Authors: Sung-Young Lee, Jaeho Yoon, Hyun-Shik Lee, Yoo-Seok Hwang, Sang-Wook Cha, Chul-Ho Jeong, Jong-Il Kim, Jae-Bong Park, Jae-Yong Lee, SungChan Kim, Mae Ja Park, Zigang Dong, Jaebong Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3146467?pdf=render