Efficacy of oral metformin in a patient with metastatic adrenocortical carcinoma: Examination of mechanisms and therapeutic implications

Although rare, adrenocortical carcinoma is among the most common tumors found in children with Li-Fraumeni syndrome and Li-Fraumeni-like syndrome, associated with germ-line mutations in the TP53 gene. In southern Brazil, one form of Li-Fraumeni syndrome, associated with childhood adrenocortical carc...

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Bibliographic Details
Main Authors: RD Peixoto, LM Gomes, TT Sousa, DJ Racy, M Shigenaga, RA Nagourney
Format: Article
Language:English
Published: SAGE Publishing 2018-01-01
Series:Rare Tumors
Online Access:https://doi.org/10.1177/2036361317749645