Importance of the Long-Chain Fatty Acid Beta-Hydroxylating Cytochrome P450 Enzyme YbdT for Lipopeptide Biosynthesis in Bacillus subtilis Strain OKB105

Importance of the Long-Chain Fatty Acid Beta-Hydroxylating Cytochrome P450 Enzyme YbdT for Lipopeptide Biosynthesis in Bacillus subtilis Strain OKB105

Bacillus species produce extracellular, surface-active lipopeptides such as surfactin that have wide applications in industry and medicine. The steps involved in the synthesis of 3-hydroxyacyl-coenzyme A (CoA) substrates needed for surfactin biosynthesis are not understood. Cell-free extracts of Bac...

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Bibliographic Details
Main Authors: Michael J. McInerney, Neil Wofford, Noha H. Youssef
Format: Article
Language:English
Published: MDPI AG 2011-03-01
Series:International Journal of Molecular Sciences
Subjects:
cytochrome P450
YbdT
long chain fatty acids
beta hydroxylation
Bacillus subtilis
surfactin
Online Access:http://www.mdpi.com/1422-0067/12/3/1767/

Internet

http://www.mdpi.com/1422-0067/12/3/1767/

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