Scaffold Modifications in Erythromycin Macrolide Antibiotics. A Chemical Minireview
Clarithromycin and congeners are important antibacterial members of the erythromycin A 14-membered macrocyclic lactone family. The macrolide scaffold consists of a multifunctional core that carries both chemically reactive and non-reactive substituents and sites. Two main approaches are used in the...
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Format: | Article |
Language: | English |
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MDPI AG
2020-08-01
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Series: | Molecules |
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Online Access: | https://www.mdpi.com/1420-3049/25/17/3941 |