Molecular Characterization of Voltage-Gated Sodium Channels and Their Relations with Paralytic Shellfish Toxin Bioaccumulation in the Pacific Oyster Crassostrea gigas

Molecular Characterization of Voltage-Gated Sodium Channels and Their Relations with Paralytic Shellfish Toxin Bioaccumulation in the Pacific Oyster Crassostrea gigas

Paralytic shellfish toxins (PST) bind to voltage-gated sodium channels (Nav) and block conduction of action potential in excitable cells. This study aimed to (i) characterize Nav sequences in Crassostrea gigas and (ii) investigate a putative relation between Nav and PST-bioaccumulation in oysters. T...

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Bibliographic Details
Main Authors: Floriane Boullot, Justine Castrec, Adeline Bidault, Natanael Dantas, Laura Payton, Mickael Perrigault, Damien Tran, Zouher Amzil, Pierre Boudry, Philippe Soudant, Hélène Hégaret, Caroline Fabioux
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Marine Drugs
Subjects:
Crassostrea gigas
sodium channel
alternative splicing
Alexandrium minutum
paralytic shellfish toxins
Online Access:http://www.mdpi.com/1660-3397/15/1/21

Internet

http://www.mdpi.com/1660-3397/15/1/21

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