Inhibition of Carrageenan-Induced Cutaneous Inflammation by PPAR Agonists Is Dependent on Hepatocyte-Specific Retinoid X Receptor Alpha

It has been proposed that PPAR-dependent, accelerated catabolism of proinflammatory mediators may contribute to the fast resolution of inflammation. Because retinoid X receptors are obligate heterodimer partners of PPARs, we investigated the impact of deleting hepatocyte-specific RXRα on the antiede...

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Bibliographic Details
Main Authors: Yu-Jui Yvonne Wan, Mostafa Z. Badr
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/PPAR/2006/96341