Syndecan-4 Promotes Epithelial Tumor Cells Spreading and Regulates the Turnover of PKCα Activity under Mechanical Stimulation on the Elastomeric Substrates

Syndecan-4 Promotes Epithelial Tumor Cells Spreading and Regulates the Turnover of PKCα Activity under Mechanical Stimulation on the Elastomeric Substrates

Background: Heparan sulfate proteoglycans (HSPGs) at the cell surface play an important role in cell adhesion, spreading, formation of focal adhesion complexes (FACs), and sensing mechanical stress. Syndecans are members of the HSPGs family and are highly expressed in various tumor cells. Syndecan-4...

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Bibliographic Details
Main Authors: Chun-Ping Huang, Chao-Min Cheng, Hong-Lin Su, Yi-Wen Lin
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Mechanotransducer
Syndecan-4
Polydimethylsiloxane
Tumor cell development
Online Access:http://www.karger.com/Article/FullText/430297

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http://www.karger.com/Article/FullText/430297

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