Neurosteroids are reduced in diabetic neuropathy and may be associated with the development of neuropathic pain [version 1; referees: 1 approved, 2 approved with reservations]
Introduction: Peripheral and central sensitisation are implicated in the development of neuropathic pain. Hypersensitivity of pain pathway neurons has been described in animal models of diabetic neuropathy, which is postulated to be related to an imbalance between inhibitory and excitatory signals w...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2016-08-01
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| Series: | F1000Research |
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| Online Access: | https://f1000research.com/articles/5-1923/v1 |