LRG1 promotes epithelial-mesenchymal transition of retinal pigment epithelium cells by activating NOX4

AIM: To investigate the effect of leucine-rich-alpha-2-glycoprotein 1 (LRG1) on epithelial-mesenchymal transition (EMT) in retinal pigment epithelium (RPE) cells, and to explore the role of NADPH oxidase 4 (NOX4). METHODS: RPE cells (ARPE-19 cell line) were treated with transforming growth factor-β1...

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Bibliographic Details
Main Authors: Li Zhou, De-Peng Shi, Wen-Juan Chu, Ling-Ling Yang, Hai-Feng Xu
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2021-03-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://ies.ijo.cn/en_publish/2021/3/20210303.pdf