CTLA-4 (+49A/G) Polymorphism in Type 1 Diabetes Children of Sudanese Population
Background Type 1 diabetes mellitus (T1DM) is an organ-specific T cell-mediated autoimmune disease, characterized by destruction of pancreatic islets. Cytotoxic lymphocyte antigen-4 (CTLA-4) is a negative regulator of T cell proliferation, thus conferring susceptibility to autoimmunity. A...
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| Format: | Article |
| Language: | English |
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Georg Thieme Verlag KG
2021-02-01
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| Series: | Global Medical Genetics |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1723008 |