In silico study of multicellular automaticity of heterogeneous cardiac cell monolayers: Effects of automaticity strength and structural linear anisotropy.

The biological pacemaker approach is an alternative to cardiac electronic pacemakers. Its main objective is to create pacemaking activity from added or modified distribution of spontaneous cells in the myocardium. This paper aims to assess how automaticity strength of pacemaker cells (i.e. their abi...

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Bibliographic Details
Main Authors: James Elber Duverger, Vincent Jacquemet, Alain Vinet, Philippe Comtois
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5877903?pdf=render