Curcumin longa extract-loaded nanoemulsion improves the survival of endotoxemic mice by inhibiting nitric oxide-dependent HMGB1 release

Background High mobility group box 1 (HMGB1) is a well-known damage-related alarmin that participates in cellular inflammatory responses. However, the mechanisms leading to HMGB1 release in inflammatory conditions and the therapeutic agents that could prevent it remain poorly understood. This study...

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Bibliographic Details
Main Authors: Min Young Ahn, Jung Seok Hwang, Su Bi Lee, Sun Ah Ham, Jinwoo Hur, Jun Tae Kim, Han Geuk Seo
Format: Article
Language:English
Published: PeerJ Inc. 2017-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/3808.pdf