Curcumin longa extract-loaded nanoemulsion improves the survival of endotoxemic mice by inhibiting nitric oxide-dependent HMGB1 release
Background High mobility group box 1 (HMGB1) is a well-known damage-related alarmin that participates in cellular inflammatory responses. However, the mechanisms leading to HMGB1 release in inflammatory conditions and the therapeutic agents that could prevent it remain poorly understood. This study...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2017-09-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/3808.pdf |