Encephalomyocarditis virus viroporin 2B activates NLRP3 inflammasome.

Nod-like receptors (NLRs) comprise a large family of intracellular pattern- recognition receptors. Members of the NLR family assemble into large multiprotein complexes, termed the inflammasomes. The NLR family, pyrin domain-containing 3 (NLRP3) is triggered by a diverse set of molecules and signals,...

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Bibliographic Details
Main Authors: Minako Ito, Yusuke Yanagi, Takeshi Ichinohe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3415442?pdf=render