Distinct mechanisms for OxLDL uptake and cellular trafficking by class B scavenger receptors CD36 and SR-BI

Distinct mechanisms for OxLDL uptake and cellular trafficking by class B scavenger receptors CD36 and SR-BI

Modified forms of LDL, including oxidized low density lipoprotein (OxLDL), contribute to macrophage lipid accumulation in the vessel wall. Despite the pathophysiological importance of uptake pathways for OxLDL, the molecular details of OxLDL endocytosis by macrophages are not well understood. Studie...

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Bibliographic Details
Main Authors: Bing Sun, Boris B. Boyanovsky, Margery A. Connelly, Preetha Shridas, Deneys R. van der Westhuyzen, Nancy R. Webb
Format: Article
Language:English
Published: Elsevier 2007-12-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
endocytosis
dynamin
scavenger receptor class B type I
oxidized low density lipoprotein
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520429062

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http://www.sciencedirect.com/science/article/pii/S0022227520429062

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