The dual impact of HIV-1 infection and aging on naïve CD4 T-cells: additive and distinct patterns of impairment.

HIV-1-infected adults over the age of 50 years progress to AIDS more rapidly than adults in their twenties or thirties. In addition, HIV-1-infected individuals receiving antiretroviral therapy (ART) present with clinical diseases, such as various cancers and liver disease, more commonly seen in olde...

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Bibliographic Details
Main Authors: Tammy M Rickabaugh, Ryan D Kilpatrick, Lance E Hultin, Patricia M Hultin, Mary Ann Hausner, Catherine A Sugar, Keri N Althoff, Joseph B Margolick, Charles R Rinaldo, Roger Detels, John Phair, Rita B Effros, Beth D Jamieson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3027697?pdf=render