Sodium bicarbonate treatment during transient or sustained lactic acidemia in normoxic and normotensive rats.

Sodium bicarbonate treatment during transient or sustained lactic acidemia in normoxic and normotensive rats.

INTRODUCTION: Lactic acidosis is a frequent cause of poor outcome in the intensive care settings. We set up an experimental model of lactic acid infusion in normoxic and normotensive rats to investigate the systemic effects of lactic acidemia per se without the confounding factor of an underlying or...

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Main Authors: Franco Valenza, Marta Pizzocri, Valentina Salice, Giorgio Chevallard, Tommaso Fossali, Silvia Coppola, Sara Froio, Federico Polli, Stefano Gatti, Francesco Fortunato, Giacomo P Comi, Luciano Gattinoni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3461035?pdf=render

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http://europepmc.org/articles/PMC3461035?pdf=render

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