Hyperbilirubinemia in Gunn Rats Is Associated with Decreased Inflammatory Response in LPS-Mediated Systemic Inflammation

Hyperbilirubinemia in Gunn Rats Is Associated with Decreased Inflammatory Response in LPS-Mediated Systemic Inflammation

Decreased inflammatory status has been reported in subjects with mild unconjugated hyperbilirubinemia. However, mechanisms of the anti-inflammatory actions of bilirubin (BR) are not fully understood. The aim of this study is to assess the role of BR in systemic inflammation using hyperbilirubinemic...

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Bibliographic Details
Main Authors: Petra Valaskova, Ales Dvorak, Martin Lenicek, Katerina Zizalova, Nikolina Kutinova-Canova, Jaroslav Zelenka, Monika Cahova, Libor Vitek, Lucie Muchova
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
bilirubin
Gunn rats
hyperbilirubinemia
inflammation
LPS
NF-κB
Online Access:https://www.mdpi.com/1422-0067/20/9/2306

Internet

https://www.mdpi.com/1422-0067/20/9/2306

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