Brain NAD Is Associated With ATP Energy Production and Membrane Phospholipid Turnover in Humans

The brain requires a large amount of energy, mostly derived from the metabolism of glucose, which decreases substantially with age and neurological diseases. While mounting evidence in model organisms illustrates the central role of brain nicotinamide adenine dinucleotide (NAD) for maintaining energ...

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Bibliographic Details
Main Authors: Bernard Cuenoud, Özlem Ipek, Maya Shevlyakova, Maurice Beaumont, Stephen C. Cunnane, Rolf Gruetter, Lijing Xin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
NAD
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2020.609517/full