Neurotoxic Anatoxin-a Can Also Exert Immunotoxicity by the Induction of Apoptosis on Carassius auratus Lymphocytes in vitro When Exposed to Environmentally Relevant Concentrations

Neurotoxic Anatoxin-a Can Also Exert Immunotoxicity by the Induction of Apoptosis on Carassius auratus Lymphocytes in vitro When Exposed to Environmentally Relevant Concentrations

Hazardous anatoxin-a (ANTX-a) is produced by freshwater algal blooms worldwide, which greatly increases the risk of consumer exposure. Although ANTX-a shows widespread neurotoxicity in aquatic animals, little is known about its mechanism of action and biotransformation in biological systems, especia...

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Bibliographic Details
Main Authors: Yuchi Zhong, Lilai Shen, Xueping Ye, Dongren Zhou, Yunyi He, Yan Li, Ying Ding, Weiqin Zhu, Jiafeng Ding, Hangjun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Physiology
Subjects:
apoptosis
ANTX-a
oxidative stress
antioxidant enzymes
fish lymphocytes
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00316/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00316/full

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