Pin1 Is Regulated by CaMKII Activation in Glutamate-Induced Retinal Neuronal Regulated Necrosis

Pin1 Is Regulated by CaMKII Activation in Glutamate-Induced Retinal Neuronal Regulated Necrosis

In our previous study, we reported that peptidyl-prolyl isomerase 1 (Pin1)-modulated regulated necrosis (RN) occurred in cultured retinal neurons after glutamate injury. In the current study, we investigated the role of calcium/calmodulin-dependent protein kinase II (CaMKII) in Pin1-modulated RN in...

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Bibliographic Details
Main Authors: Shuchao Wang, Lvshuang Liao, Yanxia Huang, Mi Wang, Hongkang Zhou, Dan Chen, Fengxia Liu, Dan Ji, Xiaobo Xia, Bing Jiang, Jufang Huang, Kun Xiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
regulated necrosis
glutamate
calcium
CaMKII
Pin1
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00276/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00276/full

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