The Signaling Mechanism of TGF-β Induced Bovine Mammary Epithelial Cell Apoptosis

The present study showed that Transforming growth factor beta 1 (TGF-β1) can induce apoptosis of bovine mammary epithelial cells. This apoptosis was also observed with phosphorylation of Smad2/3 within 0.5–2 h. Afterwards the signal transferred into the nucleus. Moreover, intracellular free Ca2+ con...

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Bibliographic Details
Main Authors: He-Shuang Di, Li-Gang Wang, Gen-Lin Wang, Lei Zhou, Yuan-Yuan Yang
Format: Article
Language:English
Published: Asian-Australasian Association of Animal Production Societies 2012-03-01
Series:Asian-Australasian Journal of Animal Sciences
Subjects:
Online Access:http://www.ajas.info/upload/pdf/25-41.pdf