Lung Marginated and Splenic Murine Resident Neutrophils Constitute Pioneers in Tissue-Defense During Systemic E. coli Challenge

Lung Marginated and Splenic Murine Resident Neutrophils Constitute Pioneers in Tissue-Defense During Systemic E. coli Challenge

The rapid response of neutrophils throughout the body to a systemic challenge is a critical first step in resolution of bacterial infection such as Escherichia coli (E. coli). Here we delineated the dynamics of this response, revealing novel insights into the molecular mechanisms using lung and sple...

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Bibliographic Details
Main Authors: Goda Juzenaite, Judith Secklehner, Juho Vuononvirta, Yoseph Helbawi, John B. G. Mackey, Charlotte Dean, James A. Harker, Leo M. Carlin, Sara Rankin, Katia De Filippo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
intravital microscopy
E. coli challenge
neutrophil activation
intravascular neutrophils
splenic resident neutrophils
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.597595/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.597595/full

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