HER2 expression, gene amplification and chromosome 17 copy number in primary pancreatic adenocarcinoma, matastatic lymph node and metastasis

HER2 expression or gene amplification is crucial for performing targeted theraphy. We assessed p185<sup>HER2</sup> (p185) expression, HER2 amplification and copy number of chromosome 17 centromere (CEP17) in pancreatic adenocarcinoma (PAC). We analyzed 26 tumours at diagnosis, 21 metasta...

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Main Authors: S. Boccardo, S. Salvi, P. Ferro, S. Asioli, N. Gorji, P. Dessanti, D. Gianquinto, A. Vigani, M.C. Franceschini, M. Truini, A. Morabito, M.P. Pistillo, F. Fedeli, S. Roncella
Format: Article
Language:English
Published: PAGEPress Publications 2011-01-01
Series:Journal of Biological Research
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Online Access:http://www.pagepressjournals.org/index.php/jbr/article/view/4641