Renal biomarkers of acute kidney injury in response to increasing intermittent hypoxia episodes in the neonatal rat

Abstract Background We tested the hypotheses that: 1) early exposure to increasing episodes of clinically relevant intermittent hypoxia (IH) is detrimental to the developing kidneys; and 2) there is a critical number of daily IH episodes which will result in irreparable renal damage that may involve...

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Bibliographic Details
Main Authors: Anano Zangaladze, Charles L. Cai, Matthew Marcelino, Jacob V. Aranda, Kay D. Beharry
Format: Article
Language:English
Published: BMC 2021-09-01
Series:BMC Nephrology
Subjects:
Online Access:https://doi.org/10.1186/s12882-021-02507-7