The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programed Cell Death and Presents Therapeutic Potential in Experimental Cutaneous Leishmaniasis.

Among neglected tropical diseases, leishmaniasis is one of the most important ones, affecting more than 12 million people worldwide. The available treatments are not well tolerated, and present diverse side effects, justifying the search for new therapeutic compounds. In the present study, the activ...

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Main Authors: Eduardo S Yamamoto, Bruno L S Campos, Jéssica A Jesus, Márcia D Laurenti, Susan P Ribeiro, Esper G Kallás, Mariana Rafael-Fernandes, Gabriela Santos-Gomes, Marcelo S Silva, Deborah P Sessa, João H G Lago, Débora Levy, Luiz F D Passero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4699202?pdf=render