Evidence of compromised blood-spinal cord barrier in early and late symptomatic SOD1 mice modeling ALS.

The blood-brain barrier (BBB), blood-spinal cord barrier (BSCB), and blood-cerebrospinal fluid barrier (BCSFB) control cerebral/spinal cord homeostasis by selective transport of molecules and cells from the systemic compartment. In the spinal cord and brain of both ALS patients and animal models, in...

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Bibliographic Details
Main Authors: Svitlana Garbuzova-Davis, Samuel Saporta, Edward Haller, Irina Kolomey, Steven P Bennett, Huntington Potter, Paul R Sanberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2075163?pdf=render