Haptoglobin and sickle cell polymorphisms and risk of active trachoma in Gambian children.

BACKGROUND:Susceptibility and resistance to trachoma, the leading infectious cause of blindness, have been associated with a range of host genetic factors. In vitro studies of the causative organism, Chlamydia trachomatis, demonstrate that iron availability regulates its growth, suggesting that host...

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Bibliographic Details
Main Authors: Mathilde Savy, Branwen J Hennig, Conor P Doherty, Anthony J Fulford, Robin Bailey, Martin J Holland, Giorgio Sirugo, Kirk A Rockett, Dominic P Kwiatkowski, Andrew M Prentice, Sharon E Cox
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2884021?pdf=render