Pomegranate flower extract bidirectionally regulates the proliferation, differentiation and apoptosis of 3T3-L1 cells through regulation of PPARγ expression mediated by PI3K-AKT signaling pathway

Pomegranate flower extract bidirectionally regulates the proliferation, differentiation and apoptosis of 3T3-L1 cells through regulation of PPARγ expression mediated by PI3K-AKT signaling pathway

Objectives: Pomegranate flower is a kind of uygur medicine with anti - type 2 diabetes, anti - lipid, anti - inflammation, anti - oxidation. We investigated the effect of pomegranate flower extract (PFE) on the proliferation, differentiation and apoptosis of 3T3-L1 preadipocytes, as well as the effe...

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Bibliographic Details
Main Authors: Tong Li, Ling Zhang, Chen Jin, Yao Xiong, Yu-Yao Cheng, Kang Chen
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Pomegranate flowers
Akt-PI3K signaling pathway
PPARγ
Lipid accumulation
Apoptosis
Active component
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220309628

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http://www.sciencedirect.com/science/article/pii/S0753332220309628

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