Highly sensitive proximity mediated immunoassay reveals HER2 status conversion in the circulating tumor cells of metastatic breast cancer patients

Highly sensitive proximity mediated immunoassay reveals HER2 status conversion in the circulating tumor cells of metastatic breast cancer patients

<p>Abstract</p> <p>Background</p> <p>The clinical benefits associated with targeted oncology agents are generally limited to subsets of patients. Even with favorable biomarker profiles, many patients do not respond or acquire resistance. Existing technologies are ineffe...

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Bibliographic Details
Main Authors: Kim Phillip, Liu Xinjun, Lee Tani, Liu Limin, Barham Robert, Kirkland Richard, Leesman Glen, Kuller Anne, Ybarrondo Belen, Ng Shi-Chung, Singh Sharat
Format: Article
Language:English
Published: BMC 2011-12-01
Series:Proteome Science
Subjects:
Companion diagnostics
Collaborative enzyme enhanced reactive-immunoassay
Metastatic breast cancer, Circulating tumor cells
HER2 conversion
Online Access:http://www.proteomesci.com/content/9/1/75

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http://www.proteomesci.com/content/9/1/75

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