Anabolic effects and inhibition of interleukin 6 production induced by neridronate on human osteoblasts

Bisphosphonates (BPs) are pharmacological compounds widely used in the treatment of a variety of bone-related diseases, particularly where the bone-turnover is skewed in favour of osteolysis. The mechanisms by which BPs reduce bone-resorption directly acting on osteoclasts (OCs) are now largely clar...

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Bibliographic Details
Main Authors: S. Niccolini, F. Chellini, F. Baldi, P. Ferrata, D. Gambera, C. Capperucci, B. Frediani, A. Spreafico, L. Bocchi, R. Marcolongo
Format: Article
Language:English
Published: PAGEPress Publications 2011-09-01
Series:Reumatismo
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/283