High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence.

Cholera is the prime example of blood-group-dependent diseases, with individuals of blood group O experiencing the most severe symptoms. The cholera toxin is the main suspect to cause this relationship. We report the high-resolution crystal structures (1.1-1.6 Å) of the native cholera toxin B-pentam...

Full description

Bibliographic Details
Main Authors: Julie Elisabeth Heggelund, Daniel Burschowsky, Victoria Ariel Bjørnestad, Vesna Hodnik, Gregor Anderluh, Ute Krengel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4833353?pdf=render