Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans

Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans

Bis(monoacylglycerol)phosphate (BMP) is a phospholipid that is crucial for lipid degradation and sorting in acidic organelles. Genetic and drug-induced lysosomal storage disorders (LSDs) are associated with increased BMP concentrations in tissues and in the circulation. Data on BMP in disorders othe...

Full description

Bibliographic Details
Main Authors: Gernot F. Grabner, Nermeen Fawzy, Maria A. Pribasnig, Markus Trieb, Ulrike Taschler, Michael Holzer, Martina Schweiger, Heimo Wolinski, Dagmar Kolb, Angela Horvath, Rolf Breinbauer, Thomas Rülicke, Roland Rabl, Achim Lass, Vanessa Stadlbauer, Birgit Hutter-Paier, Rudolf E. Stauber, Peter Fickert, Rudolf Zechner, Gunther Marsche, Thomas O. Eichmann, Robert Zimmermann
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Journal of Lipid Research
Subjects:
nonalcoholic fatty liver disease
obesity
lysosomal storage disorders
phospholipids
lysobisphosphatidic acid
α/β-hydrolase domain-containing 6
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520322719

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520322719

Similar Items