Thymosin β10 promotes tumor-associated macrophages M2 conversion and proliferation via the PI3K/Akt pathway in lung adenocarcinoma

Thymosin β10 promotes tumor-associated macrophages M2 conversion and proliferation via the PI3K/Akt pathway in lung adenocarcinoma

Abstract Background Thymosin β10 (TMSB10) has been reported to play a protumorigenic role in a majority of solid cancers. However, the existence of TMSB10 in immune microenvironment may contribute to the pathogenesis of lung adenocarcinoma has not been previously explored. Method TAMs-associated TMS...

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Bibliographic Details
Main Authors: Jun Zeng, Xianggui Yang, Li Yang, Wancheng Li, Yaxin Zheng
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Respiratory Research
Subjects:
Thymosin β10
Macrophages
Proliferation
Phenotype conversion
PI3K/Akt
Lung adenocarcinoma
Online Access:https://doi.org/10.1186/s12931-020-01587-7

Internet

https://doi.org/10.1186/s12931-020-01587-7

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