T cell receptor repertoire among women who cleared and failed to clear cervical human papillomavirus infection: An exploratory proof-of-principle study.

T cell receptor repertoire among women who cleared and failed to clear cervical human papillomavirus infection: An exploratory proof-of-principle study.

It is unknown why a minority of women fail to clear human papillomavirus (HPV) and develop precancer/cancer. Differences in T-cell receptor (TCR) repertoires may identify HPV16-infected women at highest-risk for progression to cancer. We conducted a proof-of-principle study nested within the Guanaca...

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Bibliographic Details
Main Authors: Krystle A Lang Kuhs, Shih-Wen Lin, Xing Hua, Mark Schiffman, Robert D Burk, Ana Cecilia Rodriguez, Rolando Herrero, Christian C Abnet, Neal D Freedman, Ligia A Pinto, David Hamm, Harlan Robins, Allan Hildesheim, Jianxin Shi, Mahboobeh Safaeian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5791954?pdf=render

Internet

http://europepmc.org/articles/PMC5791954?pdf=render

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