Evaluation of immune protection against Toxoplasma gondii infection in mice induced by a multi-antigenic DNA vaccine containing TgGRA24, TgGRA25 and TgMIC6

Toxoplasma gondii infection is prevalent in humans and animals worldwide. In this study, recombinant eukaryotic expression plasmids (pVAX-GRA24, pVAX-GRA25 and pVAX-MIC6) were constructed, and then injected into Kunming mice intramuscularly, as cocktailed plasmids or as single-gene plasmids. We eval...

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Bibliographic Details
Main Authors: Xu Xiao-Pei, Liu Wen-Ge, Xu Qian-Ming, Zhu Xing-Quan, Chen Jia
Format: Article
Language:English
Published: EDP Sciences 2019-01-01
Series:Parasite
Subjects:
Online Access:https://www.parasite-journal.org/articles/parasite/full_html/2019/01/parasite190055/parasite190055.html