Molecular classification of amyotrophic lateral sclerosis by unsupervised clustering of gene expression in motor cortex

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and ultimately fatal neurodegenerative disease, caused by the loss of motor neurons in the brain and spinal cord. Although 10% of ALS cases are familial (FALS), the majority are sporadic (SALS) and probably associated to a multifactorial e...

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Bibliographic Details
Main Authors: Eleonora Aronica, Frank Baas, Anand Iyer, Anneloor L.M.A. ten Asbroek, Giovanna Morello, Sebastiano Cavallaro
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Neurobiology of Disease
Subjects:
ALS
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114003738