Endogenous neurotrophins and Trk signaling in diffuse large B cell lymphoma cell lines are involved in sensitivity to rituximab-induced apoptosis.

BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) is a common and often fatal malignancy. Immunochemotherapy, a combination of rituximab to standard chemotherapy, has resulted in improved survival. However a substantial proportion of patients still fail to reach sustained remission. We have previous...

Full description

Bibliographic Details
Main Authors: Cynthia Bellanger, Lydie Dubanet, Marie-Claude Lise, Anne-Laure Fauchais, Dominique Bordessoule, Marie-Odile Jauberteau, Danielle Troutaud
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3208602?pdf=render